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Recombinant CLDN18.2 (Zolbetuximab Biosimilar) anticorps

L’anticorps Humanized Monoclonal anti-CLDN18.2 (Zolbetuximab Biosimilar) a été validé pour FACS et in vivo. Il convient pour détecter CLDN18.2 (Zolbetuximab Biosimilar) dans des échantillons de Humain.
N° du produit ABIN7795131

Aperçu rapide pour Recombinant CLDN18.2 (Zolbetuximab Biosimilar) anticorps (ABIN7795131)

Antigène

CLDN18.2 (Zolbetuximab Biosimilar)

Type d'anticorp

Recombinant Antibody

Reactivité

Humain

Hôte

  • 1
  • 1
  • 1
  • 1
Humanized

Clonalité

  • 2
  • 2
Monoclonal

Conjugué

  • 4
Cet anticorp CLDN18.2 (Zolbetuximab Biosimilar) est non-conjugé

Application

  • 2
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS), In vivo Studies (in vivo)

Classe de qualité

Research Grade
  • Expression System

    Mammalian cells

    Fonction

    Zolbetuximab Biosimilar, Claudin 18.2 Monoclonal Antibody

    Attributs du produit

    What is zolbetuximab biosimilar research grade? Zolbetuximab is a humanized monoclonal antibody directed against the human protein Claudin 18.2 (the isoform 2 of Claudin), and potentially used for the treatment of gastrointestinal adenocarcinomas and pancreatic tumors. Zolbetuximab is an Fc-engineered, humanized, monoclonal antibody (IgG1κ isotype). Zolbetuximab biosimilar uses the same protein sequences as the potential therapeutic antibody zolbetuximab . Claudin-18 in humans is a protein encoded by the CLDN18 gene. The CLDN18 protein belongs to the large claudin family of proteins, which form tight junction strands in epithelial cells. Isoform 2 (Claudin 18.2) is abundant in gastric tumors.

    Purification

    Protein A or G affinity column

    Pureté

    >95 % by reducing SDS-PAGE

    niveau d'endotoxine

    < 1 EU per 1 mg of the protein by the LAL method

    Immunogène

    Human Claudin 18.2
  • Indications d'application

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    > 3 mg/mL

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.
  • Antigène

    CLDN18.2 (Zolbetuximab Biosimilar)

    Autre désignation

    Zolbetuximab Biosimilar

    Classe de substances

    Biosimilar
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